La Phase 2 de ce programme de recherche (2008-2011) a exploré la performance cognitive de volontaires humains exposés à un champ magnétique de 3 mT. Cette étude a également analysé l'impact de l'exposition sur l'activité cérébrale humaine mesurée par Imagerie par Résonance Magnétique fonctionnelle (IRMf).
Articles
Legros A., Modolo J., Brown S., Robertson J., Thomas A. W. (2015) Effects of a 60 Hz magnetic field exposure up to 3000 µT on human brain activation as measured by functional magnetic resonance imaging. PlosOne, DOI: 10.1371/journal.pone.0132024. [PMCID: PMC4516358]
Modolo J., Legros A., Beuter A. (2014) The next move in neuromodulation therapy: a question of timing. Frontiers in Computational Neuroscience, 8:162. [PMCID: PMC4327509]
Legros A., Miller J., Modolo J., Corbacio M., Robertson J., Goulet D., Lambrozo J., Plante M., Souques M., Prato F.S., Thomas A.W. (2013) Efeitos de campos eletromagneticos no sistema nervoso humano. Electricidade Moderna, 475: 94-105.
Modolo J., Thomas A. W., Legros A. (2013) Neural mass modeling of power-line magnetic fields effects on brain activity. Frontiers in Computational Neuroscience, 7(34):1-15. doi:10.3389/fncom.2013.00034. Abstract Available
Modolo J., Thomas A. W., Legros A. (2013) Possible mechanisms of synaptic plasticity modulation by 60 Hz magnetic fields. Electromagnetic Biology and Medicine, 32(2):137-144. [PMID: 23675616]
Corbacio M., Brown S., Dubois S., Beuter A., Prato F.S., Thomas A.W., Legros A. (2011) Human Cognitive Performance in a 3 mT Power-Line Frequency Magnetic Field. Bioelectromagnetics, 32(8): 620-633. Abstract Available
Legros A., Miller J., Modolo J., Corbacio M., Robertson J., Goulet D., Lambrozo J., Plante M., Souques M., Prato F.S., Thomas A.W. (2011) Multi-modalities investigation of 60 Hz magnetic field effects on the human central nervous system. Electra, 256: 4-18. Abstract Available
Rapports
Legros A., Modolo J., Beuter A., Thomas A.W. Effets d'un Champ Magnétique de 3000 µT à 60 Hz sur les Performances Cognitives et l'Activité Cérébrale Fonctionnelle Mesurée par IRMf Chez l'Humain - Phase II / Effects of a 3000 µT, 60 Hz Magnetic Field on Human Cognitive Performances and Functional Cerebral Activation - Phase II. 374 pgs. Phase II final report for EDF/RTE - Hydro Québec, Lawson Health Research Institute.
Conférences, Résumés et Proceedings
Legros A., Modolo J., Thomas A.W. Extremely low frequency magnetic field exposure and neuromodulation in humans. Invited plenary presentation to the joint Meeting of the European Bioelectromagnetics Association and of the Bioelectromagnetics Society (BioEM 2013), Thessaloniki, Greece, June 10th – 14th 2013. Abstract Available
Legros A., Modolo J., Goulet D., Plante M., Souques M., Deschamps F., Prato F., Lambrozo J., Thomas A.W. Review on studies of brain physiology and EMF exposure PART I: ELF - Human studies - power frequencies. 2012 Workshop on EMF & Health Risk Research, Monte Verita, Switzerland, October 21-26th 2012.
Legros A., Modolo J., Dubois S., Thomas A. W. Human exposure to power-line frequency magnetic fields of up to 50 milliTesla: where is the threshold for an acute neurophysiological effect? 7th International Workshop on Biological Effects of EMF, Valetta, Malta, October 8-12th 2012.
Modolo J., Thomas A. W., Legros A. Biophysical mathematical models: a new window on the effects of extremely low-frequency magnetic fields on human brain activity. Proceeding: 7th International Workshop on Biological Effects of EMF, University of Malta, October 8-12 2012. Abstract Available
Modolo J., Thomas A.W., Legros A. The application of neural field theory to understand the effect of exposure to electric and magnetic field stimuli on brain activity. Progress in Neural Field Theory 2012, Reading, United Kingdom, April 19-21st 2012.
Modolo J., Thomas A.W., Stodilka R.Z., Legros A. Evidence for changes in brain synaptic plasticity induced by exposure to extremely low-frequency magnetic fields. 34th meeting of the Bioelectromagnetics Society, Brisbane, Australia, June 17-22nd 2012.
Modolo J., Thomas A. W., Legros A. A mechanism-based synaptic plasticity model that may help to explain large-scale neural network dynamics. Neurodynamics Workshop, Edinburgh, March 5-7th 2012.
Modolo J., Beuter A., Cates J., Jog M., Buhran A., Prato F. S., Thomas A. W., Legros A. Bidirectional coupling between motor cortex and muscular activity during resting tremor in Parkinson's disease. Movement Disorders Society International Congress, Toronto, June 5-9th 2011.
Legros A., Miller J., Modolo J., Corbacio M., Robertson J., Goulet D., Lambrozo J., Plante M., Souques M., Prato F.S., Thomas A.W. Multi-modalities investigation of 60 Hz magnetic field effects on the human central nervous system. 2nd International Conference on EMF-ELF (CIGRE). March 24-25th 2011, Paris, France. Abstract Available
Juen N., Modolo, J., Thomas, A. W., Legros A. Is Human Brain Activity Modulated by Powerline Frequency Magnetic Field Exposure? European Bioelectromagnetics Association international congress, Rome, Italy, February 21-24th, 2011.
Legros A., Corbacio M., Miller J., Modolo J., Juen N., Goulet D., Lambrozo J., Plante M., Souques M., Prato F.S., Thomas A. W. From Behavioral Monitoring to Functional Brain Imaging: Impact of a 60 Hz Magnetic Field at 1.8, 3 and up to 50 mT in Humans. European Bioelectromagnetics Association international congress, Rome, Italy, February 21-24th, 2011.
Corbacio M., Brown S., Dubois S., Weller J., Beuter A., Goulet D., Lambrozo J., Plante M., Souques M., Prato F.S., Thomas A.W., Legros A. Effects of a 60 Hz, 3000 Microtesla Magnetic Field on Human Cognitive Processing. Bioelectromagnetics Society 32nd Annual Meeting, Seoul, South Korea, June 2010.
Corbacio M., Brown S., Dubois S., Juen N., Weller J., Beuter A., Goulet D., Lambrozo J., Plante M., Souques M., Prato F.S., Thomas A.W., Legros A.G. Is Human Cognitive Performance Modulated by a Power-Line Frequency Magnetic Field? 6th International Workshop on Biological Effects of Electromagnetic Fields, Bodrum, Turkey, October 2010. Abstract Available
Legros A., Miller J., Modolo J., Corbacio M., Robertson J., Goulet D., Lambrozo J., Plante M., Souques M., Prato F.S., Thomas A.W. Is finger tapping induced brain activation modulated by an exposure to a 60 Hz, 3000 µT magnetic field? Bioelectromagnetics Society 32nd Annual Meeting, Seoul, South Korea, June 2010.
Legros A., Miller J., Modolo J., Corbacio M., Robertson J., Goulet D., Lambrozo J., Plante M., Souques M., Prato F.S., Thomas A.W. Functional brain activation during finger tapping is modulated after a 60 Hz, 3000 µT magnetic field exposure. EMF Bordeaux Event (EBEA/URSI/COST), Bordeaux, France, May 2010.
Legros A., Miller J., Modolo J., Corbacio M., Robertson J., Goulet D., Lambrozo J., Plante M., Souques M., Prato F.S., Thomas A.W. Finger tapping induced brain activation is modulated after a 60 Hz, 3000 µT magnetic field exposure. Proceeding: 6th International Workshop on Biological Effects of Electromagnetic Fields, Bodrum, Turkey, October 2010. Abstract Available
Legros A., Miller J., Modolo J., Corbacio M., Robertson J., Cates J., Goulet D., Lambrozo J., Plante M., Souques M., Prato F.S., Thomas A.W. Modulation de l’activité cérébrale pendant une tâche de tapping après exposition à un champ magnétique de 3000 microTesla à 60 Hz. Journée scientifique Effets biologiques et sanitaires des Rayonnements Non Ionisants organisée par la Société Française de Radioprotection. Paris, France, Janvier 2011.
Modolo, J., Juen, N., Robertson J.A., Legros A., Thomas A. EEG frequency analysis of 60 Hz magnetic field exposure within the MRI. 2nd International Conference on EMF-ELF (CIGRE). March 24-25th 2011, Paris, France.
Miller J, Modolo J., Robertson J.R., Corbacio M., Dubois, S., Stodilka R., Goulet D., Lambrozo J., Plante M., Souques M., Prato F.S., Thomas A.W., Legros A. Effects of a 60 Hz Magnetic Field Exposure on Human Cortical Activity During a Mental Rotation Task as Measured by fMRI. Bioelectromagnetics Society 32nd Annual Meeting, Seoul, South Korea, June 2010.
Miller J., Modolo J., Corbacio M., Robertson J.R. , Goulet D., Lambrozo J., Plante M., Souques M., Prato F.S., Thomas A.W., Legros A. Functional Magnetic Resonance Imaging of the Effects of a 60 Hz 3000 µT Magnetic Field on Resting State Brain Blood Flow. 19th annual meeting of the ISMRM, Montréal, Canada, May 7-13th 2011.
Miller J., Modolo J., Corbacio M., Goulet D., Lambrozo J., Plante M., Souques M., Prato F.S., Thomas A.W., Legros A. Exposure to a 60 Hz 3000 μT magnetic field has an effect on resting brain blood flow: A functional magnetic resonance imaging study. Bioelectromagnetics Society 33rd Annual Meeting, Halifax, Canada, June 12-17th 2011.
Modolo J., Stodilka R., Prato F., Thomas A. W., Legros A. Frequency preference in a Hodgkin-Huxley neuron interacting with extremely low-frequency magnetic fields: implications for biological effects. European Bioelectromagnetics Association international congress, Rome, Italy, February 21-24th, 2011.
Miller J., Modolo J., Robertson J., Corbacio M., Goulet D., Lambrozo J., Plante M., Souques M., Prato F.S., Thomas A.W., Legros A. Functional Magnetic Resonance Imaging of the Effects of a 60 Hz Magnetic Field on Human Cortical Activity During a Mental Rotation Task. 6th International Workshop on Biological Effects of Electromagnetic Fields, Bodrum, Turkey, October 2010. Abstract Available
Miller J., Modolo J., Corbacio M., Robertson J.R. , Goulet D., Lambrozo J., Plante M., Souques M., Prato F.S., Thomas A.W., Legros A. Effets de l'exposition à un champ magnétique à 60 Hz sur l’activité cérébrale mesurés par IRMf pendant une tâche de rotation mentale. Congrès national de la Société Française de Radioprotection. Tours, France, 31-23 juin 2011.
Modolo J. Juen N., Robertson J. A., Thomas A. W., Legros A. EEG frequency analysis of 60 Hz magnetic field exposure within the MRI. CIGRE conference, Paris, March 24-25th (2011). Abstract Available
Modolo J., Thomas A. W., Stodilka R. Z., Prato F. S., Legros A. Modulation of neuronal activity with extremely low-frequency magnetic fields: insights from biophysical modeling. IEEE Fifth International Conference on Bio-Inspired Computing: Theories and Applications, 2010. Abstract Available
